Postdoctoral Research Fellow - In vivo Pharmacology
Job DescriptionBe a part of the legacy:
Postdoctoral Research Fellow ProgramOur Research Laboratories' Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment.
With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.
The In Vivo Pharmacology - Oncology group within the Department of Quantitative Biosciences (QB) is seeking a Post Doctoral Fellow with expertise in cancer biology to join our Boston-based Exploratory Discovery team.
The successful candidate will have a track record of innovative and collaborative research, demonstrated through peer-reviewed publications.
They will be able to work independently but will also be expected to proactively collaborate with colleagues across multiple disciplines.
Primary responsibilities include designing and executing in vitro and in vivo preclinical studies to characterize the effects of our company's oncology drug candidates.
The candidate will present their data at internal and external conferences as well as publish their findings in a peer-reviewed journal.
The candidate will be an active participant in the positive and critical scientific dialogue that is necessary to progress our oncology drug discovery programs.
An ability to communicate clearly and collaborate effectively with colleagues in the QB, Oncology, and Immunology groups as well as scientists from different disciplines will be essential for success.
Responsibilities:
Assessing mechanism of action of oncology drug candidates using in vitro assays and preclinical rodent models.
Harvesting and analyzing samples collected in preclinical in vivo studies to identify biomarkers in blood, tumors, and surrogate tissues using molecular methods including but not limited to:
flow or mass cytometry, in vitro immunoassays, qPCR, ELISA, or western blotting.
Independently plan and execute studies with the primary goal of presenting data at external conferences and publishing data, ideally in a high impact journal.
Communicate and present data clearly and concisely to the appropriate teams and stakeholders.
Be able to thrive in a team environment.
Required Experience and skills:
Experience with molecular biology techniques such as flow/mass cytometry, in vitro immunology assays (eg MLR, ELIspot, etc), ELISA, and/or qPCR is desired.
Some experience designing and executing in vivo animal studies including animal handling, blood and tissue sampling and data collection analysis and interpretation is desired.
Demonstrated ability to function and communicate effectively in a multi-disciplinary environment.
Excellent problem-solving, communication, and project management skills.
Preferred Experience and skills:
Extensive expertise in cell culture and in 3D tumor models is highly desired.
Minimum education required:
Candidates must currently hold a PhD OR receive a PhD within one year in the field of cancer biology, immune-oncology, or similar discipline.
PostdocfellowNOTICE FOR INTERNAL APPLICANTSIn accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package.
To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders).
Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated.
Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
Current Employees apply HERECurrent Contingent Workers apply HEREUS and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.
Please click here if you need an accommodation during the application or hiring process.
For more information about personal rights under Equal Employment Opportunity, visit:
EEOC Know Your RightsEEOC GINA SupplementPay Transparency NondiscriminationWe are proud to be a company that embraces the value of bringing diverse, talented, and committed people together.
The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment.
We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.
We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.
Learn more about your rights, including under California, Colorado and other US State ActsSearch Firm Representatives Please Read Carefully Merck & Co.
, Inc.
, Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities.
All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.
No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place.
Where agency agreements are in place, introductions are position specific.
Please, no phone calls or emails.
Employee Status:
RegularRelocation:
DomesticVISA Sponsorship:
YesTravel Requirements:
No Travel RequiredFlexible Work Arrangements:
On-SiteShift:
1st - DayValid Driving License:
NoHazardous Material(s):
na Recommended Skills Biology Cell Cultures Data Collection Molecular Biology Oncology Problem Solving Estimated Salary: $20 to $28 per hour based on qualifications.
Postdoctoral Research Fellow ProgramOur Research Laboratories' Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment.
With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.
The In Vivo Pharmacology - Oncology group within the Department of Quantitative Biosciences (QB) is seeking a Post Doctoral Fellow with expertise in cancer biology to join our Boston-based Exploratory Discovery team.
The successful candidate will have a track record of innovative and collaborative research, demonstrated through peer-reviewed publications.
They will be able to work independently but will also be expected to proactively collaborate with colleagues across multiple disciplines.
Primary responsibilities include designing and executing in vitro and in vivo preclinical studies to characterize the effects of our company's oncology drug candidates.
The candidate will present their data at internal and external conferences as well as publish their findings in a peer-reviewed journal.
The candidate will be an active participant in the positive and critical scientific dialogue that is necessary to progress our oncology drug discovery programs.
An ability to communicate clearly and collaborate effectively with colleagues in the QB, Oncology, and Immunology groups as well as scientists from different disciplines will be essential for success.
Responsibilities:
Assessing mechanism of action of oncology drug candidates using in vitro assays and preclinical rodent models.
Harvesting and analyzing samples collected in preclinical in vivo studies to identify biomarkers in blood, tumors, and surrogate tissues using molecular methods including but not limited to:
flow or mass cytometry, in vitro immunoassays, qPCR, ELISA, or western blotting.
Independently plan and execute studies with the primary goal of presenting data at external conferences and publishing data, ideally in a high impact journal.
Communicate and present data clearly and concisely to the appropriate teams and stakeholders.
Be able to thrive in a team environment.
Required Experience and skills:
Experience with molecular biology techniques such as flow/mass cytometry, in vitro immunology assays (eg MLR, ELIspot, etc), ELISA, and/or qPCR is desired.
Some experience designing and executing in vivo animal studies including animal handling, blood and tissue sampling and data collection analysis and interpretation is desired.
Demonstrated ability to function and communicate effectively in a multi-disciplinary environment.
Excellent problem-solving, communication, and project management skills.
Preferred Experience and skills:
Extensive expertise in cell culture and in 3D tumor models is highly desired.
Minimum education required:
Candidates must currently hold a PhD OR receive a PhD within one year in the field of cancer biology, immune-oncology, or similar discipline.
PostdocfellowNOTICE FOR INTERNAL APPLICANTSIn accordance with Managers' Policy - Job Posting and Employee Placement, all employees subject to this policy are required to have a minimum of twelve (12) months of service in current position prior to applying for open positions.
If you have been offered a separation benefits package, but have not yet reached your separation date and are offered a position within the salary and geographical parameters as set forth in the Summary Plan Description (SPD) of your separation package, then you are no longer eligible for your separation benefits package.
To discuss in more detail, please contact your HRBP or Talent Acquisition Advisor.
Employees working in roles that the Company determines require routine collaboration with external stakeholders, such as customer-facing commercial, or research-based roles, will be expected to comply not only with Company policy but also with policies established by such external stakeholders (for example, a requirement to be vaccinated against COVID-19 in order to access a facility or meet with stakeholders).
Please understand that, as permitted by applicable law, if you have not been vaccinated against COVID-19 and an essential function of your job is to call on external stakeholders who require vaccination to enter their premises or engage in face-to-face meetings, then your employment may pose an undue burden to business operations, in which case you may not be offered employment, or your employment could be terminated.
Please also note that, where permitted by applicable law, the Company reserves the right to require COVID-19 vaccinations for positions, such as in Global Employee Health, where the Company determines in its discretion that the nature of the role presents an increased risk of disease transmission.
Current Employees apply HERECurrent Contingent Workers apply HEREUS and Puerto Rico Residents Only:
Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities.
Please click here if you need an accommodation during the application or hiring process.
For more information about personal rights under Equal Employment Opportunity, visit:
EEOC Know Your RightsEEOC GINA SupplementPay Transparency NondiscriminationWe are proud to be a company that embraces the value of bringing diverse, talented, and committed people together.
The fastest way to breakthrough innovation is when diverse ideas come together in an inclusive environment.
We encourage our colleagues to respectfully challenge one another's thinking and approach problems collectively.
We are an equal opportunity employer, committed to fostering an inclusive and diverse workplace.
Learn more about your rights, including under California, Colorado and other US State ActsSearch Firm Representatives Please Read Carefully Merck & Co.
, Inc.
, Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities.
All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company.
No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place.
Where agency agreements are in place, introductions are position specific.
Please, no phone calls or emails.
Employee Status:
RegularRelocation:
DomesticVISA Sponsorship:
YesTravel Requirements:
No Travel RequiredFlexible Work Arrangements:
On-SiteShift:
1st - DayValid Driving License:
NoHazardous Material(s):
na Recommended Skills Biology Cell Cultures Data Collection Molecular Biology Oncology Problem Solving Estimated Salary: $20 to $28 per hour based on qualifications.
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